Genetic characterization of Italian field strains of Schmallenberg virus based on N and NSs genes

Virus Genes. 2016 Aug;52(4):582-5. doi: 10.1007/s11262-016-1335-9. Epub 2016 Apr 8.

Abstract

Following its first identification in Germany in 2011, the Schmallenberg virus (SBV) has rapidly spread to many other European countries. Despite the wide dissemination, the molecular characterization of the circulating strains is limited to German, Belgian, Dutch, and Swiss viruses. To fill this gap, partial genetic characterization of 15 Italian field strains was performed, based on S segment genes. Samples were collected in 2012 in two different regions where outbreaks occurred during distinct epidemic seasons. The comparative sequence analysis demonstrated a high molecular stability of the circulating viruses; nevertheless, we identified several variants of the N and NSs proteins not described in other SBV isolates circulating in Europe.

Keywords: Genetic characterization; Italian strains; Nucleotide sequence; S segment; Schmallenberg virus.

MeSH terms

  • Animal Diseases / virology
  • Animals
  • Bunyaviridae Infections / veterinary
  • Bunyaviridae Infections / virology*
  • Cattle
  • Disease Outbreaks / veterinary
  • Genes, Viral / genetics*
  • Goats / virology
  • Italy
  • Orthobunyavirus / genetics*
  • Orthobunyavirus / isolation & purification*
  • Sheep / virology