[A new flavone from stems of Garcinia bracteata and its anti-TMV activity]

Zhongguo Zhong Yao Za Zhi. 2015 Nov;40(21):4205-7.
[Article in Chinese]

Abstract

A phytochemical investigation on the stems of Garcinia bracteata collected from Xishuangbanna resulted in the isolation of a new flavone. By analysis of the HRESIMS, IR, UV, 1D and 2D NMR spectra, the structure of the new compound was determined as 7-methoxy-4',6-dihydroxy-8-isobutyryl-flavone(1). Compound 1 was also tested for its anti-tobacco mosaic virus(TMV) activity. Results suggested the 1 possessed remarkable anti-TMV activity, with an inhibition rate of 28.2%.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Antiviral Agents / chemistry*
  • Antiviral Agents / isolation & purification
  • Antiviral Agents / pharmacology*
  • Drugs, Chinese Herbal / chemistry*
  • Drugs, Chinese Herbal / isolation & purification
  • Drugs, Chinese Herbal / pharmacology*
  • Flavones / chemistry*
  • Flavones / isolation & purification
  • Flavones / pharmacology*
  • Garcinia / chemistry*
  • Magnetic Resonance Spectroscopy
  • Plant Leaves / chemistry
  • Tobacco Mosaic Virus / drug effects*
  • Tobacco Mosaic Virus / growth & development

Substances

  • Antiviral Agents
  • Drugs, Chinese Herbal
  • Flavones
  • flavone