Lymphoepithelioma-like gastric carcinoma in a patient with rectal laterally spreading tumor: A case report

Oncol Lett. 2016 Apr;11(4):2491-2496. doi: 10.3892/ol.2016.4268. Epub 2016 Feb 24.

Abstract

Lymphoepithelioma-like gastric carcinoma (LELGC) is a rare neoplasm of the stomach that accounts for 1-4% of all gastric cancer cases. It is characterized by the presence of a lymphoid stroma with cells arranged primarily in micro alveolar, thin trabecular and primitive tubular patterns or isolated cells. In the present study, the case of a 50-year-old male patient with LELGC and rectal laterally spreading tumor is presented. Following endoscopic submucosal dissection, a diagnosis of carcinoma was reached and the patient underwent total radical gastrectomy. The postoperative pathological stage was IA T1bN0cM0 according to the Tumor-Node-Metastasis classification of gastric carcinoma, and the patient recovered well. The present case is reported to summarize the endoscopic and pathological characteristics of LELGC.

Keywords: Epstein-Barr virus; laterally spreading tumor; lymphoepithelioma-like gastric carcinoma; lymphoid stroma; prognosis.