Spatial Orientation and Morphology of the Pulmonary Artery: Relevance to Optimising Design and Positioning of a Continuous Pressure Monitoring Device

J Cardiovasc Transl Res. 2016 Jun;9(3):239-248. doi: 10.1007/s12265-016-9690-4. Epub 2016 Apr 13.

Abstract

Personalised treatment of heart disease requires an understanding of the patient-specific characteristics, which can vary over time. A newly developed implantable surface acoustic wave pressure sensor, capable of continuous monitoring of the left ventricle filling pressure, is a novel device for personalised management of patients with heart disease. However, a one-size-fits-all approach to device sizing will affect its positioning within the pulmonary artery and its relationship to the interrogating device on the chest wall on a patient-specific level. In this paper, we analyse the spatial orientation and morphology of the pulmonary artery and its main branches in patients who could benefit from the device and normal controls. The results could optimise the design of the sensor, its stent, and importantly its placement, ensuring long-term monitoring in patient groups.

Keywords: Device design; Morphology; Orientation; Pressure monitoring; Pulmonary artery.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Acoustics / instrumentation*
  • Adult
  • Aged
  • Arterial Pressure*
  • Blood Pressure Monitoring, Ambulatory / instrumentation*
  • Blood Pressure Monitors*
  • Case-Control Studies
  • Computed Tomography Angiography
  • Equipment Design
  • Female
  • Heart Diseases / diagnosis*
  • Heart Diseases / physiopathology
  • Humans
  • Hypertension, Pulmonary / diagnosis*
  • Hypertension, Pulmonary / physiopathology
  • Male
  • Middle Aged
  • Multidetector Computed Tomography
  • Predictive Value of Tests
  • Pulmonary Artery / diagnostic imaging
  • Pulmonary Artery / physiopathology*
  • Time Factors
  • Transducers, Pressure*
  • Ventricular Function, Left
  • Ventricular Pressure*