G2 rotavirus within an emergent VP7 evolutionary lineage circulating in children with acute diarrhea in Guangxi Province of China, 2014

Arch Virol. 2016 Jul;161(7):1987-92. doi: 10.1007/s00705-016-2852-5. Epub 2016 Apr 21.

Abstract

Routine surveillance revealed that the prevalence of P[4] rotaviruses circulating in children with acute diarrhea in Guangxi Province, China, increased in 2014. However, VP7 genotyping for these P[4] rotaviruses was unsuccessful. Exhaustive database searching and sequence analysis indicated that the G genotype of these P[4] rotaviruses was G2, and the VP7 genes clustered with recently emerging G2 strains in several countries within an emergent evolutionary lineage that was distinct from the previously designated lineages I-IV as well as lineage V including porcine rotaviruses. Further studies are essential to monitor the potential global spread of this emerging G2 rotavirus.

MeSH terms

  • Acute Disease / epidemiology
  • Amino Acid Sequence
  • Antigens, Viral / chemistry
  • Antigens, Viral / genetics*
  • Base Sequence
  • Capsid Proteins / chemistry
  • Capsid Proteins / genetics*
  • Child, Preschool
  • China / epidemiology
  • Diarrhea / epidemiology
  • Diarrhea / virology*
  • Evolution, Molecular*
  • Female
  • Genotype
  • Humans
  • Infant
  • Male
  • Molecular Sequence Data
  • Phylogeny
  • Rotavirus / chemistry
  • Rotavirus / classification
  • Rotavirus / genetics*
  • Rotavirus / isolation & purification
  • Rotavirus Infections / epidemiology
  • Rotavirus Infections / virology*
  • Sequence Alignment

Substances

  • Antigens, Viral
  • Capsid Proteins
  • VP7 protein, Rotavirus