Acute cardiac failure secondary to senile systemic amyloidosis

Age Ageing. 2016 Nov;45(6):908-909. doi: 10.1093/ageing/afw073. Epub 2016 Apr 21.

Abstract

Hereditary or senile transthyretin (TTR) cardiac amyloidosis is a rare and underestimated cause of heart failure in old patients. New diagnostic methods, particularly cardiac MRI and proteomic analysis, have been recently developed that enable both earlier identification and development of specific treatments.We report a case of cardiac amyloidosis revealed through late-onset heart failure.

Keywords: cardiac amyloidosis; heart failure; older people; senile amyloidosis; transthyretin amyloidosis.

Publication types

  • Case Reports

MeSH terms

  • Acute Disease
  • Aged, 80 and over
  • Amyloid Neuropathies, Familial / blood
  • Amyloid Neuropathies, Familial / complications*
  • Amyloid Neuropathies, Familial / diagnosis
  • Biomarkers / blood
  • Cardiomyopathies / blood
  • Cardiomyopathies / diagnosis
  • Cardiomyopathies / etiology*
  • Echocardiography
  • Female
  • Heart Failure / blood
  • Heart Failure / diagnosis
  • Heart Failure / etiology*
  • Humans
  • Magnetic Resonance Imaging
  • Predictive Value of Tests
  • Proteomics / methods

Substances

  • Biomarkers

Supplementary concepts

  • Amyloidosis, Hereditary, Transthyretin-Related