Presumed Second Focus of Lung Immunoglobulin G4-Related Disease Found to be Adenocarcinoma

Gregory D Scott; David A Sauer; Kirsten M Woolf; Mithran S Sukumar; Brandon H Tieu

doi:10.1016/j.athoracsur.2015.07.041

Presumed Second Focus of Lung Immunoglobulin G4-Related Disease Found to be Adenocarcinoma

Ann Thorac Surg. 2016 May;101(5):1965-7. doi: 10.1016/j.athoracsur.2015.07.041.

Authors

Gregory D Scott¹, David A Sauer², Kirsten M Woolf³, Mithran S Sukumar⁴, Brandon H Tieu⁵

Affiliations

¹ MD/PhD Program, Oregon Health and Science University, Portland, Oregon.
² Department of Pathology, Oregon Health and Science University, Portland, Oregon.
³ Department of Pathology/Laboratory, Portland VA Medical Center, Portland, Oregon.
⁴ Division of Cardiothoracic Surgery, Oregon Health and Science University, Portland, Oregon.
⁵ Division of Cardiothoracic Surgery, Oregon Health and Science University, Portland, Oregon. Electronic address: [email protected].

PMID: 27106428
DOI: 10.1016/j.athoracsur.2015.07.041

Abstract

We describe a patient presenting with bilateral radiologically similar lung lesions initially diagnosed as immunoglobulin (Ig) G4-related disease from biopsy of one lesion, but radiographic changes 6 months later prompted biopsy of the second lesion and showed adenocarcinoma. No case of lung IgG4-related disease and a distant lung malignancy has been previously reported. This is notable because lung IgG4-related disease often manifests in multiple thoracic locations but is diagnosed from a representative biopsy specimen.

Publication types

Case Reports

MeSH terms

Adenocarcinoma / diagnosis*
Adenocarcinoma of Lung
Humans
Immunoglobulin G / immunology*
Lung Diseases / diagnosis*
Lung Neoplasms / diagnosis*
Male
Middle Aged
Tomography, X-Ray Computed

Substances

Immunoglobulin G