[Selective bladder preservation in muscle-invasive bladder cancer by transurethral resection combined with intravesical instillation therapy: analysis of clinical effect in the elderly]

Zhonghua Yi Xue Za Zhi. 2016 Apr 26;96(16):1278-80. doi: 10.3760/cma.j.issn.0376-2491.2016.16.011.
[Article in Chinese]

Abstract

Objective: To explore the therapeutic effect and quality of life in elderly patients of muscle-invasive bladder cancer by transurethral resection combined with intravesical instillation therapy.

Methods: From January 2005 to January 2015, 136 cases were diagnosed with T2 bladder cancer by transurethralplasmakinetic therapy or transurethral laser therapy. The data of 136 cases were analyzed retrospectively.

Results: In transurethralplasmakinetic therapy group, the overall survival rate was 73.3%, the cancer-specific survival rate was 85.6%, the average survival time were 65 months. In transurethral laser therapy group, the overall survival rate was 73.9%, the cancer-specific survivalrate was 87.2%, the average survival time were 70 months. Two methods also can improve the patient's quality of life.

Conclusion: For the aged with invasive bladder cancer (T2), we could try the transurethral resection combined with intravesical instillation therapy.

MeSH terms

  • Administration, Intravesical
  • Combined Modality Therapy
  • Humans
  • Neoplasm Recurrence, Local
  • Organ Sparing Treatments*
  • Quality of Life
  • Retrospective Studies
  • Survival Rate
  • Urinary Bladder Neoplasms / drug therapy*
  • Urinary Bladder Neoplasms / surgery*