The NOTCH1/CD39 axis: a Treg trip-switch for GvHD

Leukemia. 2016 Sep;30(9):1931-4. doi: 10.1038/leu.2016.87. Epub 2016 Apr 29.

Authors

B Del Papa¹, A Pierini^{1

2}, P Sportoletti¹, S Baldoni³, D Cecchini¹, E Rosati⁴, E Dorillo¹, P Aureli¹, T Zei¹, R Iacucci Ostini¹, L Ruggeri¹, A Carotti¹, A Velardi¹, R Negrin², M F Martelli¹, F Falzetti¹, M Di Ianni³

Affiliations

¹ Division of Hematology and Clinical Immunology, Department of Medicine, University of Perugia, Perugia, Italy.
² Division of Blood and Marrow Transplantation, Department of Medicine, Stanford University, Stanford, CA, USA.
³ Hematology Section, Department of Life, Health and Environmental Sciences, University of L'Aquila, L'Aquila, Italy.
⁴ Department of Experimental Medicine, Biosciences and Medical Embryology Section, University of Perugia, Perugia, Italy.

PMID: 27125307
DOI: 10.1038/leu.2016.87

No abstract available

Publication types

Letter
Research Support, Non-U.S. Gov't

MeSH terms

Animals
Antigens, CD / immunology
Apyrase / immunology
Graft vs Host Disease / immunology*
Humans
Immune Tolerance / immunology*
Mice
Receptor, Notch1 / immunology*
T-Lymphocytes / immunology*
T-Lymphocytes, Regulatory / immunology*

Substances

Antigens, CD
Receptor, Notch1
Apyrase
CD39 antigen