Too little benefit for too much toxicity: rethinking the adjuvant development model in colon cancer

Curr Opin Oncol. 2016 Jul;28(4):345-7. doi: 10.1097/CCO.0000000000000298.
No abstract available

Publication types

  • Editorial

MeSH terms

  • Antineoplastic Combined Chemotherapy Protocols / adverse effects
  • Antineoplastic Combined Chemotherapy Protocols / therapeutic use*
  • Biomarkers, Tumor / genetics
  • Chemotherapy, Adjuvant
  • Colonic Neoplasms / drug therapy*
  • Colonic Neoplasms / genetics
  • Colonic Neoplasms / pathology
  • DNA Damage
  • Fluorouracil / administration & dosage
  • Fluorouracil / adverse effects
  • Fluorouracil / therapeutic use*
  • Gene Expression Regulation, Neoplastic / drug effects
  • Humans
  • Neoplasm Staging
  • Outcome Assessment, Health Care / methods*

Substances

  • Biomarkers, Tumor
  • Fluorouracil