Diversity of beta-papillomavirus at anogenital and oral anatomic sites of men: The HIM Study

Virology. 2016 Aug:495:33-41. doi: 10.1016/j.virol.2016.04.031. Epub 2016 May 7.

Abstract

Our goal was to describe prevalence of β-HPVs at three anatomic sites among 717 men from Brazil, Mexico and US enrolled in the HPV Infection in Men (HIM) Study. β-HPVs were genotyped using Luminex technology. Overall, 77.7%, 54.3% and 29.3% men were positive for any β-HPV at the genitals, anal canal, and oral cavity, respectively. Men from US and Brazil were significantly less likely to have β-HPV at the anal canal than men from Mexico. Older men were more likely to have β-HPV at the anal canal compared to younger men. Prevalence of β-HPV at the oral cavity was significantly associated with country of origin and age. Current smokers were significantly less likely to have β-HPV in the oral cavity than men who never smoked. Lack of associations between β-HPV and sexual behaviors may suggest other routes of contact such as autoinoculation which need to be explored further.

Keywords: Anogenital; Cutaneous human papillomavirus; HIM Study; Males; Oral; Prevalence.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Anal Canal / virology*
  • Betapapillomavirus / classification*
  • Betapapillomavirus / genetics
  • Brazil / epidemiology
  • DNA, Viral
  • Female
  • Genitalia, Male / virology*
  • Genotype
  • Humans
  • Male
  • Middle Aged
  • Mouth / virology*
  • Papillomavirus Infections / epidemiology*
  • Papillomavirus Infections / virology*
  • Population Surveillance
  • Prevalence
  • Risk Factors
  • Sexual Behavior
  • United States / epidemiology
  • Young Adult

Substances

  • DNA, Viral