Successful Desensitization to Cetuximab in a Patient With a Positive Skin Test to Cetuximab and Specific IgE to Alpha-gal

J Investig Allergol Clin Immunol. 2016;26(2):132-4. doi: 10.18176/jiaci.0031.
No abstract available

Keywords: Alpha-gal; Cetuximab; Desensitization; Drug hypersensitivity.

Publication types

  • Case Reports

MeSH terms

  • Antineoplastic Agents / therapeutic use*
  • Autoantibodies / blood*
  • Carcinoma, Squamous Cell / drug therapy
  • Carcinoma, Squamous Cell / immunology
  • Carcinoma, Squamous Cell / secondary
  • Cetuximab / therapeutic use*
  • Desensitization, Immunologic / methods*
  • Drug Administration Schedule
  • Humans
  • Immunoglobulin E / blood*
  • Lung Neoplasms / drug therapy
  • Lung Neoplasms / immunology
  • Lung Neoplasms / secondary
  • Male
  • Middle Aged
  • Pharyngeal Neoplasms / drug therapy
  • Pharyngeal Neoplasms / immunology
  • Pharyngeal Neoplasms / pathology
  • Pyriform Sinus / drug effects
  • Pyriform Sinus / immunology
  • Pyriform Sinus / pathology
  • Skin Tests
  • alpha-Galactosidase / blood
  • alpha-Galactosidase / immunology*

Substances

  • Antineoplastic Agents
  • Autoantibodies
  • Immunoglobulin E
  • GLA protein, human
  • alpha-Galactosidase
  • Cetuximab