Deferasirox AUC efficacy cutoff and role of pharmacogenetics

Eur J Clin Pharmacol. 2016 Sep;72(9):1155-7. doi: 10.1007/s00228-016-2070-9. Epub 2016 May 18.
No abstract available

Publication types

  • Letter

MeSH terms

  • Area Under Curve
  • Benzoates / blood
  • Benzoates / pharmacokinetics*
  • Benzoates / therapeutic use*
  • Deferasirox
  • Female
  • Genotype
  • Humans
  • Iron Chelating Agents / pharmacokinetics*
  • Iron Chelating Agents / therapeutic use*
  • Male
  • Pharmacogenetics
  • Polymorphism, Single Nucleotide
  • Treatment Outcome
  • Triazoles / blood
  • Triazoles / pharmacokinetics*
  • Triazoles / therapeutic use*
  • beta-Thalassemia / blood
  • beta-Thalassemia / drug therapy*
  • beta-Thalassemia / genetics
  • beta-Thalassemia / metabolism

Substances

  • Benzoates
  • Iron Chelating Agents
  • Triazoles
  • Deferasirox