Actinomycosis after allogeneic hematopoietic stem cell transplantation despite penicillin prophylaxis

Transpl Infect Dis. 2016 Aug;18(4):595-600. doi: 10.1111/tid.12549. Epub 2016 Jul 5.

Abstract

Actinomycosis is a rare chronic and multifaceted disease caused by Actinomyces species frequently mimicking malignancy or other chronic granulomatous lung diseases. We report 4 original presentations of actinomycosis arising under supposed penicillin prophylaxis in allogeneic stem cell transplantation recipients.

Keywords: Actinomyces; actinomycosis; allogeneic hematopoietic stem cell transplantation; penicillin.

Publication types

  • Case Reports

MeSH terms

  • Actinomyces / isolation & purification
  • Actinomycosis / diagnostic imaging
  • Actinomycosis / etiology*
  • Actinomycosis / microbiology
  • Actinomycosis / prevention & control*
  • Adult
  • Anti-Bacterial Agents / administration & dosage
  • Anti-Bacterial Agents / therapeutic use*
  • Antibiotic Prophylaxis*
  • Bronchoalveolar Lavage Fluid / microbiology
  • Female
  • Hematopoietic Stem Cell Transplantation / adverse effects*
  • Humans
  • Lung Diseases / diagnostic imaging
  • Lung Diseases / etiology*
  • Lung Diseases / microbiology
  • Lung Diseases / prevention & control*
  • Male
  • Middle Aged
  • Penicillins / administration & dosage
  • Penicillins / therapeutic use
  • Tomography, X-Ray Computed
  • Transplantation, Homologous / adverse effects

Substances

  • Anti-Bacterial Agents
  • Penicillins