Effect of timing of cannulation on outcome for pediatric extracorporeal life support

Pediatr Surg Int. 2016 Jul;32(7):665-9. doi: 10.1007/s00383-016-3901-6. Epub 2016 May 24.

Abstract

Purpose: Literature reports worse outcomes for operations performed during off-hours. As this has not been studied in pediatric extracorporeal life support (ECLS), we compared complications based on the timing of cannulation..

Methods: This is a retrospective review of 176 pediatric ECLS patients between 2004 and 2015. Patients cannulated during daytime hours (7:00 A.M. to 7:00 P.M., M-F) were compared to off-hours (nighttime or weekend) using t-test and Chi-square.

Results: The most common indications for ECLS were congenital diaphragmatic hernia (33 %) and persistent pulmonary hypertension (23 %). When comparing regular hours (40 %) to off-hours cannulation (60 %), there were no significant differences in central nervous system complications, hemorrhage (extra-cranial), cannula repositioning, conversion from venovenous to venoarterial, mortality on ECLS, or survival-to-discharge. The overall complication rate was slightly lower in the off-hours group (45.7 % versus 61.9 %, P = 0.034).

Conclusion: Outcomes were not significantly worse for patients undergoing ELCS cannulation during off-hours compared to normal weekday working hours.

Keywords: Cannulation; Extracorporeal membrane oxygenation; Outcomes; Timing.

MeSH terms

  • Adolescent
  • Catheterization / standards*
  • Child
  • Child, Preschool
  • Congenital Abnormalities / therapy*
  • Extracorporeal Membrane Oxygenation / methods*
  • Female
  • Humans
  • Infant
  • Infant, Newborn
  • Male
  • Retrospective Studies
  • Time Factors