Fatty replacement of spinal bone marrow due to radiation: demonstration by dual energy quantitative CT and MR imaging

J Comput Assist Tomogr. 1989 May-Jun;13(3):463-5. doi: 10.1097/00004728-198905000-00018.

Abstract

Dual energy CT and quantitative magnetic resonance (MR) imaging were used to evaluate marrow changes due to radiation. The bright signal intensity seen on MR was shown by the two quantitative techniques to be due to a threefold increase in the marrow fat content compared with nonradiated levels and to a normal control. Fat estimates by MR and dual energy CT were in excellent agreement. Single energy CT overestimates the amount of bone loss in the radiation field. Dual energy CT and quantitative MR can be used to correct this error.

Publication types

  • Case Reports
  • Comparative Study
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Adipose Tissue / diagnostic imaging*
  • Adipose Tissue / pathology*
  • Adult
  • Bone Marrow / analysis
  • Bone Marrow Diseases / diagnosis*
  • Bone Marrow Diseases / etiology
  • Humans
  • Lumbar Vertebrae / analysis
  • Magnetic Resonance Imaging*
  • Male
  • Minerals / analysis
  • Osteoradionecrosis / diagnosis
  • Plasmacytoma / radiotherapy
  • Radiation Injuries / diagnosis*
  • Spinal Diseases / diagnosis
  • Spinal Diseases / etiology
  • Spinal Neoplasms / radiotherapy
  • Tomography, X-Ray Computed*

Substances

  • Minerals