[Anticoagulation use in older patients with atrial fibrillation in a cardio-geriatric unit]

Ann Cardiol Angeiol (Paris). 2016 Sep;65(4):245-9. doi: 10.1016/j.ancard.2016.04.025. Epub 2016 May 27.
[Article in French]

Abstract

Objective: Older people with atrial fibrillation (AF) have an increased embolic risk but they are less frequently treated with anticoagulants. We wanted to assess our current practice in a specialized service.

Patients and methods: Prospective observational study including all patients older than 75 years admitted during 3 months in a cardio-geriatric unit. Patients' embolic risk (CHADS2 score), hemorrhagic risk (HAS-BLED score), anti-thrombotic treatment at arrival and any modification afterwards, were analyzed.

Results: Thirty-four patients were included (mean age: 85 years). AF was known in 28 patients, of whom 20 were under anticoagulant therapy at their admission (10 fluindione, 9 warfarine, 1 dabigatran), 4 received aspirin and 4 no anti-thrombotic treatment. Only the treatment of one of these patients was modified, replacing aspirin by warfarin. AF was newly diagnosed in 6 patients, of whom anticoagulation were initiated in 4 patients (3 warfarine, 1 fluindione). Finally, 9 patients (26%) left the hospital without anticoagulant treatment. Reasons given by their attending doctors were: advanced dementia (4 patients), estimated excessive hemorrhagic risk (4), and estimated low embolic risk (1). There was a clear trend to initiate anticoagulation more frequently in patients with a newly diagnosed AF (P=0.09) CONCLUSIONS: A substantial proportion of older patients with AF do not receive anticoagulant therapy, even after having been admitted to a specialized service. Advanced dementia and hemorrhagic risk are the reasons most frequently given for that.

Keywords: Anticoagulants; Atrial fibrillation; Fibrillation atriale; Hemorrhagic risk; Older patients; Patient âgé; Risque hémorragique.

Publication types

  • Observational Study

MeSH terms

  • Aged
  • Aged, 80 and over
  • Anticoagulants / therapeutic use*
  • Atrial Fibrillation / diagnosis
  • Atrial Fibrillation / drug therapy*
  • Cross-Sectional Studies
  • Drug Utilization
  • Female
  • France
  • Hospital Units
  • Humans
  • Male
  • Prospective Studies
  • Stroke / prevention & control

Substances

  • Anticoagulants