Does caspase-12 suppress inflammasome activation?

Nature. 2016 Jun 2;534(7605):E1-4. doi: 10.1038/nature17649.

Authors

Lieselotte Vande Walle^{1

2}, Daniel Jiménez Fernández^{1

2

3}, Dieter Demon^{1

2}, Naomi Van Laethem^{1

2}, Filip Van Hauwermeiren^{1

2}, Hanne Van Gorp^{1

2}, Nina Van Opdenbosch^{1

2}, Nobuhiko Kayagaki⁴, Mohamed Lamkanfi^{1

2}

Affiliations

¹ Inflammation Research Center, VIB, Ghent, B-9052, Belgium.
² Department of Internal Medicine, Ghent University, Ghent, B-9000, Belgium.
³ Medical Biotechnology Center, VIB, Ghent, B-9000, Belgium.
⁴ Department of Physiological Chemistry, Genentech, South San Francisco, California 94080, USA.

PMID: 27251234
DOI: 10.1038/nature17649

No abstract available

Publication types

Letter
Comment

MeSH terms

Animals
Caspases / deficiency*
Caspases / metabolism*
Humans
Listeria monocytogenes / immunology*
Sepsis / immunology*
Sepsis / microbiology*

Substances

Caspases