Abstract
Evaluation of the pro versus antioxidant activity of ascorbate regarding Cu(Aβ) induced reactive oxygen species production in the context of Alzheimer's disease shows that a protective activity can only be observed at high ascorbate concentration for exogenous molecules but not for the amyloid-β peptide itself.
MeSH terms
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Alzheimer Disease*
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Amyloid beta-Peptides*
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Antioxidants*
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Ascorbic Acid*
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Coordination Complexes*
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Copper*
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Coumarins
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Oxidative Stress*
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Reactive Oxygen Species
Substances
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Amyloid beta-Peptides
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Antioxidants
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Coordination Complexes
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Coumarins
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Reactive Oxygen Species
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Copper
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Ascorbic Acid
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coumarin-3-carboxylic acid