How do I best manage insomnia and other sleep disorders in older adults with cancer?

J Geriatr Oncol. 2016 Nov;7(6):413-421. doi: 10.1016/j.jgo.2016.05.003. Epub 2016 Jun 4.

Abstract

Insomnia is common in older adults with cancer, with a reported prevalence of 19-60% in prior studies. Cancer treatments are associated with increased risk of insomnia or aggravation of pre-existing insomnia symptoms, and patients who are receiving active cancer treatments are more likely to report insomnia. Insomnia can lead to significant physical and psychological consequences with increased mortality. We discuss physiological sleep changes in older adults, and illustrated the various sleep disorders. We present a literature review on the prevalence and the effects of insomnia on the quality of life in older adults with cancer. We discuss the risk factors and presented a theoretical framework of insomnia in older adults with cancer. We present a case study to illustrate the assessment and management of insomnia in older adults with cancer, comparing and contrasting a number of tools for sleep assessment. There are currently no guidelines on the treatment of sleep disorders in older adults with cancer. We present an algorithm developed at the City of Hope Comprehensive Cancer Center by a multidisciplinary team for managing insomnia, using evidence-based pharmacologic and non-pharmacologic interventions.

Keywords: Insomnia; Non-pharmacological interventions; Pharmacological interventions; Prevalence.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Aged
  • Algorithms
  • Ambulatory Care
  • Critical Pathways
  • Female
  • Humans
  • Neoplasms / complications*
  • Patient Care Team
  • Quality of Life
  • Risk Factors
  • Sleep Apnea Syndromes / complications
  • Sleep Apnea Syndromes / physiopathology
  • Sleep Initiation and Maintenance Disorders / complications
  • Sleep Initiation and Maintenance Disorders / physiopathology
  • Sleep Initiation and Maintenance Disorders / therapy*
  • Sleep Stages / physiology