Abstract
In the absence of acquired or secondary immunosuppression, mutations causing failure to properly activate the IL-12/IFN-γ pathway, NF-κB, or STAT3 should be excluded in patients presenting with severe histoplasmosis.
Publication types
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Case Reports
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Letter
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Research Support, N.I.H., Extramural
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Research Support, N.I.H., Intramural
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Research Support, Non-U.S. Gov't
MeSH terms
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Histoplasmosis / genetics
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Histoplasmosis / immunology*
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Humans
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I-kappa B Kinase / immunology
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Immunologic Deficiency Syndromes / genetics
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Immunologic Deficiency Syndromes / immunology*
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Male
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Middle Aged
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Mutation / genetics
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NF-kappa B / genetics
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NF-kappa B / immunology*
Substances
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NF-kappa B
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I-kappa B Kinase