Discrepancies between selected Pareto optimal plans and final deliverable plans in radiotherapy multi-criteria optimization

Archonteia Kyroudi; Kristoffer Petersson; Sarah Ghandour; Marc Pachoud; Oscar Matzinger; Mahmut Ozsahin; Jean Bourhis; François Bochud; Raphaël Moeckli

doi:10.1016/j.radonc.2016.05.018

Discrepancies between selected Pareto optimal plans and final deliverable plans in radiotherapy multi-criteria optimization

Radiother Oncol. 2016 Aug;120(2):346-8. doi: 10.1016/j.radonc.2016.05.018. Epub 2016 Jun 3.

Authors

Archonteia Kyroudi¹, Kristoffer Petersson¹, Sarah Ghandour², Marc Pachoud², Oscar Matzinger², Mahmut Ozsahin³, Jean Bourhis³, François Bochud¹, Raphaël Moeckli¹

Affiliations

¹ Institute of Radiation Physics (IRA), Lausanne University Hospital, Switzerland.
² Department of Radiation Oncology, Hôpital Riviera-Chablais, Vevey, Switzerland.
³ Department of Radiation Oncology, Lausanne University Hospital, Switzerland.

PMID: 27267047
DOI: 10.1016/j.radonc.2016.05.018

Abstract

Multi-criteria optimization provides decision makers with a range of clinical choices through Pareto plans that can be explored during real time navigation and then converted into deliverable plans. Our study shows that dosimetric differences can arise between the two steps, which could compromise the clinical choices made during navigation.

Keywords: Deliverable; Multi-criteria optimization; Navigated; Pareto fronts.

MeSH terms

Carcinoma, Non-Small-Cell Lung / radiotherapy*
Humans
Lung Neoplasms / radiotherapy*
Male
Prostatic Neoplasms / radiotherapy*
Radiometry
Radiotherapy Dosage
Radiotherapy Planning, Computer-Assisted / methods*
Radiotherapy Planning, Computer-Assisted / standards
Radiotherapy, Intensity-Modulated
Retrospective Studies