Novel heterozygous mutation in YAP1 in a family with isolated ocular colobomas

Ophthalmic Genet. 2017 May-Jun;38(3):281-283. doi: 10.1080/13816810.2016.1188122. Epub 2016 Jun 7.
No abstract available

Publication types

  • Case Reports
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adaptor Proteins, Signal Transducing / genetics*
  • Amino Acid Sequence
  • Base Sequence
  • Coloboma / diagnosis
  • Coloboma / genetics*
  • Exome / genetics
  • Genes, Dominant
  • Heterozygote
  • Humans
  • Iris / abnormalities*
  • Iris / pathology
  • Male
  • Molecular Sequence Data
  • Mutation*
  • Pedigree
  • Phosphoproteins / genetics*
  • Retina / abnormalities*
  • Retina / pathology
  • Tomography, Optical Coherence
  • Transcription Factors
  • Visual Acuity / physiology
  • YAP-Signaling Proteins
  • Young Adult

Substances

  • Adaptor Proteins, Signal Transducing
  • Phosphoproteins
  • Transcription Factors
  • YAP-Signaling Proteins
  • YAP1 protein, human