Inappropriate ICD shocks do not induce pro-arrhythmic electrocardiographic changes in men

Scand Cardiovasc J. 2017 Feb;51(1):47-52. doi: 10.1080/14017431.2016.1197418. Epub 2016 Jun 30.

Abstract

Objectives: Longer-term electrocardiographic effects of multiple inappropriate ICD shocks were investigated to study their hypothesized pro-arrhythmic potential.

Design: Thirteen male patients with ischemic cardiomyopathy who received ≥2 inappropriate shocks within 24 h and for whom 12-lead ECGs were available both before and within 72h after the inappropriate shocks were analyzed. Exclusion criteria included continuous ventricular pacing, underlying AF, events within 6 weeks after lead implantation and concomitant acute medical problems.

Results: A total of 149 inappropriate shocks (mean 11 ± 19) were received. There were no significant differences in any of the measured intervals or morphological indices, nor was there a correlation between the "before-after" differences and the number of shocks received. Non-significant changes showed Percentage of Loop Area increase and relative T-wave Residuum decrease while the opposite changes have previously been associated with arrhythmic risk.

Conclusions: No potentially pro-arrhythmic electrocardiographic changes were found 19 h after multiple inappropriate shocks.

Keywords: Electrocardiography; implantable cardioverter-defibrillator; inappropriate shocks.

MeSH terms

  • Action Potentials
  • Aged
  • Arrhythmias, Cardiac / diagnosis
  • Arrhythmias, Cardiac / etiology*
  • Arrhythmias, Cardiac / physiopathology
  • Cardiomyopathies / diagnosis
  • Cardiomyopathies / etiology
  • Cardiomyopathies / physiopathology
  • Cardiomyopathies / therapy*
  • Defibrillators, Implantable / adverse effects*
  • Electric Countershock / adverse effects*
  • Electric Countershock / instrumentation*
  • Electrocardiography
  • Electroshock*
  • Equipment Design
  • Equipment Failure*
  • Heart Conduction System / physiopathology*
  • Heart Rate
  • Humans
  • Male
  • Middle Aged
  • Myocardial Ischemia / complications
  • Risk Assessment
  • Risk Factors
  • Time Factors
  • Treatment Outcome