Enhanced Visualization of Optimal Cerebral Perfusion Pressure Over Time to Support Clinical Decision Making

Crit Care Med. 2016 Oct;44(10):e996-9. doi: 10.1097/CCM.0000000000001816.

Abstract

Objective: Cerebrovascular reactivity can provide a continuously updated individualized target for management of cerebral perfusion pressure, termed optimal cerebral perfusion pressure. The objective of this project was to find a way of improving the optimal cerebral perfusion pressure methodology by introducing a new visualization method.

Data sources: Four severe traumatic brain injury patients with intracranial pressure monitoring.

Data extraction: Data were collected and pre-processed using ICM+ software.

Data synthesis: Sequential optimal cerebral perfusion pressure curves were used to create a color-coded maps of autoregulation - cerebral perfusion pressure relationship evolution over time.

Conclusions: The visualization method addresses some of the main drawbacks of the original methodology and might bring the potential for its clinical application closer.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Brain Injuries / physiopathology*
  • Cerebrovascular Circulation / physiology*
  • Clinical Decision-Making*
  • Homeostasis / physiology
  • Humans
  • Intracranial Pressure / physiology*
  • Monitoring, Physiologic / methods*
  • Trauma Severity Indices