Reply to "Uveal melanoma cells are resistant to EZH2 inhibition regardless of BAP1 status"
Nat Med
.
2016 Jun 7;22(6):578-9.
doi: 10.1038/nm.4094.
Authors
Lindsay M LaFave
1
2
,
Wendy Béguelin
3
,
Richard Koche
4
5
,
Matt Teater
3
,
Barbara Spitzer
1
6
,
Alan Chramiec
4
,
Efthymia Papalexi
1
,
Matthew D Keller
1
,
Todd Hricik
1
,
Katerina Konstantinoff
1
,
Jean-Baptiste Micol
1
,
Benjamin Durham
1
,
Sarah K Knutson
7
,
John E Campbell
7
,
Gil Blum
8
9
,
Xinxu Shi
10
,
Emma H Doud
11
,
Andrei V Krivtsov
4
,
Young Rock Chung
1
,
Inna Khodos
12
,
Elisa de Stanchina
12
,
Ouathek Ouerfelli
10
,
Prasad S Adusumilli
13
,
Paul M Thomas
11
,
Neil L Kelleher
11
,
Minkui Luo
8
,
Heike Keilhack
7
,
Omar Abdel-Wahab
1
14
,
Ari Melnick
3
,
Scott A Armstrong
4
5
6
,
Ross L Levine
1
4
14
Affiliations
1
Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, New York, USA.
2
Gerstner Sloan Kettering School of Biomedical Sciences, New York, New York, USA.
3
Department of Hematology-Oncology, Weill Cornell Medical College, New York, New York, USA.
4
The Center for Epigenetics Research, Memorial Sloan Kettering Cancer Center, New York, New York, USA.
5
Cancer Biology and Genetics Program, Memorial Sloan Kettering Cancer Center, New York, New York, USA.
6
Department of Pediatrics, Memorial Sloan Kettering Cancer Center, New York, New York, USA.
7
Epizyme, Inc., Cambridge, Massachusetts, USA.
8
Chemical Biology Program, Memorial Sloan Kettering Cancer Center, New York, New York.
9
Tri-Institutional Program in Chemical Biology, Memorial Sloan Kettering Cancer Center, New York, New York, USA.
10
Chemical Synthesis Core, Memorial Sloan Kettering Cancer Center, New York, New York, USA.
11
Proteomics Center of Excellence, Northwestern University, Evanston, Illinois, USA.
12
Anti-Tumor Assessment Core, Memorial Sloan Kettering Cancer Center, New York, New York, USA.
13
Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, New York, USA.
14
Leukemia Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, New York, USA.
PMID:
27270773
DOI:
10.1038/nm.4094
No abstract available
Publication types
Letter
Comment
MeSH terms
Humans
Melanoma*
Tumor Suppressor Proteins
Ubiquitin Thiolesterase
Uveal Neoplasms*
Substances
Tumor Suppressor Proteins
Ubiquitin Thiolesterase
Supplementary concepts
Uveal melanoma
Grants and funding
P30 CA008748/CA/NCI NIH HHS/United States