Lung density standard deviations obtained using high-pitch dual-source computed tomography are valid predictors of bronchopulmonary dysplasia in preterm infants

Clin Imaging. 2016 Jul-Aug;40(4):594-600. doi: 10.1016/j.clinimag.2016.02.010. Epub 2016 Feb 17.

Abstract

Purpose: This study aimed to validate standard deviations of lung densities obtained using high-pitch dual-source computed tomography (DSCT) densitometry as indices of bronchopulmonary dysplasia (BPD) severity in premature infants.

Methods: Data of preterm, late preterm group, and early term groups were evaluated. Mean and median standard deviations (SDmean, SDmedian) of CT lung density (CTLD) were calculated from CT images.

Results: SDmean of CTLD in infants with severe BPD was significantly higher than that of infants without BPD (198.1 vs. 140.9, respectively; P=.002).

Conclusions: Study results support using high-pitch DSCT for BPD diagnosis and quantitative evaluation in prematurity.

Keywords: BPD; Bronchopulmonary dysplasia; Dual-source CT; High-pitch; Prematurity.

Publication types

  • Observational Study

MeSH terms

  • Bronchopulmonary Dysplasia / diagnostic imaging*
  • Humans
  • Infant
  • Infant, Newborn
  • Infant, Premature
  • Lung / diagnostic imaging*
  • Male
  • Predictive Value of Tests
  • Prospective Studies
  • Tomography, X-Ray Computed / methods*