A genetic score combining CYP450 2C19 and 3A4 genotypes to predict voriconazole plasma exposure?

Int J Antimicrob Agents. 2016 Aug;48(2):221-2. doi: 10.1016/j.ijantimicag.2016.05.002. Epub 2016 Jun 7.

Authors

Elodie Gautier-Veyret¹, Xavier Fonrose², Françoise Stanke-Labesque²

Affiliations

¹ Laboratoire de Pharmacologie-Toxicologie, Centre Hospitalier Universitaire Grenoble Alpes, CS 10217, Grenoble CEDEX 9 F-38043, France. Electronic address: [email protected].
² Laboratoire de Pharmacologie-Toxicologie, Centre Hospitalier Universitaire Grenoble Alpes, CS 10217, Grenoble CEDEX 9 F-38043, France.

PMID: 27318623
DOI: 10.1016/j.ijantimicag.2016.05.002

No abstract available

Publication types

Letter

MeSH terms

Antifungal Agents / pharmacokinetics*
Cytochrome P-450 CYP2C19 / genetics*
Cytochrome P-450 CYP3A / genetics*
Cytochrome P-450 CYP3A Inhibitors / pharmacology*
Genotype*
Humans
Plasma / chemistry*
Voriconazole / pharmacokinetics*

Substances

Antifungal Agents
Cytochrome P-450 CYP3A Inhibitors
CYP2C19 protein, human
Cytochrome P-450 CYP2C19
Cytochrome P-450 CYP3A
CYP3A4 protein, human
Voriconazole