Lipid-modifying effects of nutraceuticals: An evidence-based approach

Nutrition. 2016 Nov-Dec;32(11-12):1179-92. doi: 10.1016/j.nut.2016.04.007. Epub 2016 May 17.

Abstract

The present review provides an up-to-date summary of the findings on the lipid-lowering effects of the most important nutraceuticals and functional foods. Based on current knowledge, nutraceuticals might exert significant lipid-lowering, and their use has several advantages: A number of important questions remain to be addressed, including whether longer durations of therapy would result in a better response and the exact safety profile of nutraceuticals, especially at doses higher than those consumed in an average diet. Additionally, data regarding the effects of nutraceutical supplementation on the incidence of cardiovascular outcomes are lacking, and it is not clear whether additional lipid lowering by nutraceuticals can modify the residual cardiovascular risk that remains after statin therapy.

Keywords: Atherogenic dyslipidemia; Functional foods; Lipids; Nutraceuticals.

Publication types

  • Review

MeSH terms

  • Anthocyanins / therapeutic use
  • Berberine / therapeutic use
  • Biological Products / therapeutic use
  • Dietary Fats, Unsaturated / therapeutic use
  • Dietary Fiber / therapeutic use
  • Dietary Supplements*
  • Dyslipidemias / blood
  • Dyslipidemias / diet therapy
  • Dyslipidemias / drug therapy
  • Evidence-Based Medicine
  • Garlic
  • Hibiscus
  • Humans
  • Hypolipidemic Agents / therapeutic use*
  • Lipids / blood
  • Phytosterols / therapeutic use
  • Probiotics / therapeutic use
  • Resveratrol
  • Stilbenes / therapeutic use

Substances

  • Anthocyanins
  • Biological Products
  • Dietary Fats, Unsaturated
  • Dietary Fiber
  • Hypolipidemic Agents
  • Lipids
  • Phytosterols
  • Stilbenes
  • red yeast rice
  • Berberine
  • Resveratrol