Six new isolates of human immunodeficiency virus type 2 (HIV-2) and the molecular characterization of one (HIV-2CAM2)

J Gen Virol. 1989 Feb:70 ( Pt 2):479-84. doi: 10.1099/0022-1317-70-2-479.

Abstract

We report the isolation of human immunodeficiency virus type 2 (HIV-2) from each of six West Africans with AIDS-related complex or AIDS. One isolate (HIV-2CAM2) was molecularly cloned and shown by restriction mapping to differ in seven out of 22 sites from the prototype HIV-2ROD. Nevertheless, by a number of serological criteria these isolates are all clearly HIV-2.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • AIDS-Related Complex / microbiology
  • Acquired Immunodeficiency Syndrome / microbiology
  • Blotting, Southern
  • DNA, Viral / genetics
  • Guinea-Bissau / ethnology
  • HIV Antibodies / analysis
  • HIV Antigens / analysis
  • HIV-2 / genetics
  • HIV-2 / immunology
  • HIV-2 / isolation & purification*
  • Humans
  • Restriction Mapping

Substances

  • DNA, Viral
  • HIV Antibodies
  • HIV Antigens