Use of antiretroviral treatment among people living with HIV in Australia between 1997 and 2012

AIDS Care. 2017 Jan;29(1):61-66. doi: 10.1080/09540121.2016.1198751. Epub 2016 Jun 21.

Abstract

Current international targets aim for 90% of people diagnosed with HIV to be on antiretroviral treatment (ART). This paper aims to identify sociodemographic and attitudinal factors associated with ART non-use over time in three samples of Australian people living with HIV (PLHIV). Data for this paper were derived from an Australian cross-sectional survey of PLHIV that was repeated at three different time points: 1997, 2003, and 2012. There were approximately 1000 respondents to each survey (n = 3042 in total). The survey included approximately 250 items related broadly to health and well-being, ART use, and attitudes towards ART use. Univariate and multivariate logistic regression analyses were used. While the proportion of participants using ART increased between 1997 and 2012 (78.8-87.6%, p < .001), there was a decrease between 1997 and 2003 to 70.6% (p < .001). Factors linked to ART non-use remained steady over those 15 years. In all cohorts, people less likely to be using ART were younger and had a more recent diagnosis of HIV. In 2003 and 2012, people in full-time employment were less likely to be using ART, while those whose main source of income was a pension or social security were more likely to be using ART. Multivariate models showed that, at each time point, a belief in the health benefits of delayed ART uptake was associated with non-use. These findings suggest that there may be barriers to ART uptake that have persisted over time despite changes to clinical guidelines that now encourage early uptake.

Keywords: Antiretroviral therapy; Australia; antiretroviral therapy delayed uptake; antiretroviral therapy non-use.

MeSH terms

  • Adolescent
  • Adult
  • Age Factors
  • Aged
  • Aged, 80 and over
  • Anti-HIV Agents / therapeutic use*
  • Australia
  • Cross-Sectional Studies
  • Employment
  • Female
  • HIV Infections / diagnosis
  • HIV Infections / drug therapy*
  • Health Knowledge, Attitudes, Practice*
  • Humans
  • Medication Adherence
  • Middle Aged
  • Pensions
  • Social Security
  • Surveys and Questionnaires
  • Time Factors
  • Young Adult

Substances

  • Anti-HIV Agents