Vaginal implantation metastasis of endometrial carcinoma: A case report

Oncol Lett. 2016 Jul;12(1):513-515. doi: 10.3892/ol.2016.4656. Epub 2016 Jun 1.

Abstract

Endometrial cancer is the most common malignancy of the female reproductive system. The three common spread patterns of endometrial cancer are local invasion, lymphatic spread and hematogenous spread. Vaginal metastasis occurs by submucosal lymphatic or vascular metastases in ~10% of patients with clinical stage I disease. Vaginal implantation metastasis of endometrial cancer is extremely rare. Here we present a case of endometrial carcinoma (International Federation of Gynecology and Obstetrics stage IA) spread to the vagina by implantation metastasis as opposed to any of the methods mentioned above. This conclusion was confirmed mainly from pathological examination. This case highlights the occurrence of vaginal implantation metastasis of endometrial carcinoma. Certain changes may be applied during surgery to prevent implantation metastasis in patients with endometrial cancer.

Keywords: endometrial carcinoma; postmenopausal bleeding; surgery; vaginal bleeding; vaginal implantation metastasis.