Multimodality imaging of locally recurrent and metastatic cervical cancer: emphasis on histology, prognosis, and management

Kye Jin Park; Marta Braschi-Amirfarzan; Pamela J DiPiro; Angela A Giardino; Jyothi P Jagannathan; Stephanie A Howard; Atul B Shinagare; Katherine M Krajewski

doi:10.1007/s00261-016-0825-5

Multimodality imaging of locally recurrent and metastatic cervical cancer: emphasis on histology, prognosis, and management

Abdom Radiol (NY). 2016 Dec;41(12):2496-2508. doi: 10.1007/s00261-016-0825-5.

Authors

Kye Jin Park¹, Marta Braschi-Amirfarzan^{2

3}, Pamela J DiPiro^{2

3}, Angela A Giardino^{2

3}, Jyothi P Jagannathan^{2

3}, Stephanie A Howard^{2

3}, Atul B Shinagare^{2

3}, Katherine M Krajewski^{4

5}

Affiliations

¹ Department of Radiology and Research Institute of Radiology Asan Medical Center, University of Ulsan College of Medicine, 86 Asanbyeongwon-gil, Songpa-gu, Seoul, 138-736, Korea.
² Department of Imaging, Dana Farber Cancer Institute, Harvard Medical School, 450 Brookline Avenue, Boston, MA, 02215, USA.
³ Department of Radiology, Brigham and Women's Hospital, Harvard Medical School, 75 Francis Street, Boston, MA, 02115, USA.
⁴ Department of Imaging, Dana Farber Cancer Institute, Harvard Medical School, 450 Brookline Avenue, Boston, MA, 02215, USA. [email protected].
⁵ Department of Radiology, Brigham and Women's Hospital, Harvard Medical School, 75 Francis Street, Boston, MA, 02115, USA. [email protected].

PMID: 27357415
DOI: 10.1007/s00261-016-0825-5

Abstract

The management of recurrent and metastatic cervical cancer is evolving in concert with the available advanced imaging techniques and molecular targeted therapy. The purpose of this review is to provide an overview of imaging and treatment of cervical cancer patients with locoregional recurrence and metastatic disease, with emphasis on characteristic patterns of spread based on histology (squamous cell carcinoma and other subtypes), prognostic factors, diagnosis, and treatment response assessment, as well as updated therapeutic options.

Keywords: Cervical cancer; Histologic subtypes; Local recurrence; Metastasis.

Publication types

Review

MeSH terms

Female
Humans
Multimodal Imaging*
Neoplasm Metastasis
Neoplasm Recurrence, Local
Neoplasm Staging
Prognosis
Uterine Cervical Neoplasms / diagnostic imaging*
Uterine Cervical Neoplasms / pathology*
Uterine Cervical Neoplasms / therapy