A pseudoisochromosome 18q and an isodicentric chromosome 18

C Floore; A Robertson; I Samuel; N Williamson; D R McLeod; G Hoganson; J J Hoo

doi:10.1111/j.1399-0004.1989.tb02971.x

A pseudoisochromosome 18q and an isodicentric chromosome 18

Clin Genet. 1989 Jun;35(6):450-4. doi: 10.1111/j.1399-0004.1989.tb02971.x.

Authors

C Floore¹, A Robertson, I Samuel, N Williamson, D R McLeod, G Hoganson, J J Hoo

Affiliation

¹ Department of Pediatrics, University of Illinois, Chicago.

PMID: 2736793
DOI: 10.1111/j.1399-0004.1989.tb02971.x

Abstract

A case of pseudoisochromosome 18q of prezygotic origin and a case of isodicentric chromosome 18 of postzygotic origin are presented to validate the differentiation between a true isochromosome and a pseudoisochromosome. This differentiation may be useful in elucidating the mechanism of the origin of an isochromosome.

Publication types

Case Reports

MeSH terms

Abnormalities, Multiple / genetics*
Abnormalities, Multiple / pathology
Chromosome Aberrations*
Chromosome Banding
Chromosomes, Human, Pair 18*
Female
Humans
Infant, Newborn