Transferrin receptor 1: a target for antibody-mediated cancer therapy

Immunotherapy. 2016 Sep;8(9):991-4. doi: 10.2217/imt-2016-0050. Epub 2016 Jul 4.
No abstract available

Keywords: CD71; antibody effector functions; cancer immunotherapy; cytotoxic antibody; drug delivery; iron deprivation; receptor-mediated endocytosis; transferrin receptor 1.

Publication types

  • Editorial
  • Research Support, N.I.H., Extramural

MeSH terms

  • Animals
  • Antibodies / therapeutic use*
  • Antibody-Dependent Cell Cytotoxicity
  • Antigens, CD / immunology
  • Antigens, CD / metabolism*
  • Antigens, Neoplasm / immunology
  • Antigens, Neoplasm / metabolism*
  • Cell Proliferation
  • Clinical Trials as Topic
  • Humans
  • Immunotherapy / methods*
  • Immunotoxins / therapeutic use
  • Iron / metabolism
  • Neoplasms / immunology
  • Neoplasms / therapy*
  • Receptors, Transferrin / immunology
  • Receptors, Transferrin / metabolism*

Substances

  • Antibodies
  • Antigens, CD
  • Antigens, Neoplasm
  • CD71 antigen
  • Immunotoxins
  • Receptors, Transferrin
  • Iron