The S128N mutation combined with an additional potential N-linked glycosylation site at residue 133 in hemagglutinin affects the antigenicity of the human H7N9 virus

Emerg Microbes Infect. 2016 Jul 6;5(7):e66. doi: 10.1038/emi.2016.66.

Authors

Wanli Liu¹, Tian Bai², Jinlei Guo², Xinlan Li¹, Lei Yang², Xiaojun Wang¹, Junfeng Guo², Xin Ma¹, Xiyan Li², Hongbin Liu¹, Jianfang Zhou², Dayan Wang², Yue-Long Shu²

Affiliations

¹ The Center for Disease Control and Prevention, Urumqi, Xinjiang Uygur Autonomous Region 830001, China.
² National Institute for Viral Disease Control and Prevention, Collaboration Innovation Center for Diagnosis and Treatment of Infectious Diseases, Chinese Center for Disease Control and Prevention, Key Laboratory for Medical Virology, National Health and Family Planning Commission, Beijing 102206, China.

No abstract available

Publication types

Letter

MeSH terms

Aged
Antigens, Viral* / chemistry
Antigens, Viral* / genetics
Antigens, Viral* / immunology
Female
Glycosylation
Hemagglutinin Glycoproteins, Influenza Virus / chemistry
Hemagglutinin Glycoproteins, Influenza Virus / genetics*
Hemagglutinin Glycoproteins, Influenza Virus / immunology*
Humans
Influenza A Virus, H7N9 Subtype / genetics*
Influenza A Virus, H7N9 Subtype / isolation & purification*
Influenza, Human / virology
Mutation*

Substances

Antigens, Viral
Hemagglutinin Glycoproteins, Influenza Virus