A new fun and robust version of an fMRI localizer for the frontotemporal language system

Cogn Neurosci. 2017 Jul;8(3):167-176. doi: 10.1080/17588928.2016.1201466. Epub 2016 Jul 7.

Abstract

A set of brain regions in the frontal, temporal, and parietal lobes supports high-level linguistic processing. These regions can be reliably identified in individual subjects using fMRI, by contrasting neural responses to meaningful and structured language stimuli vs. stimuli matched for low-level properties but lacking meaning and/or structure. We here present a novel version of a language 'localizer,' which should be suitable for diverse populations including children and/or clinical populations who may have difficulty with reading or cognitively demanding tasks. In particular, we contrast responses to auditorily presented excerpts from engaging interviews or stories, and acoustically degraded versions of these materials. This language localizer is appealing because it uses (a) naturalistic and engaging linguistic materials, (b) auditory presentation,

Keywords: Language; brain imaging methods; fMRI; functional localizers; individual subject analyses.

Publication types

  • Research Support, N.I.H., Extramural

MeSH terms

  • Adolescent
  • Adult
  • Brain Mapping / methods*
  • Cerebral Cortex / diagnostic imaging
  • Cerebral Cortex / physiology*
  • Female
  • Humans
  • Language*
  • Magnetic Resonance Imaging / methods*
  • Male
  • Speech Perception / physiology*
  • Young Adult