Skin testing, graded challenge, and desensitization to von Willebrand factor (VWF) products in type III von Willebrand disease (VWD)

J Allergy Clin Immunol Pract. 2016 Sep-Oct;4(5):1006-8. doi: 10.1016/j.jaip.2016.05.017. Epub 2016 Jul 9.

Abstract

This is the first report of skin testing, graded challenge and desensitization for VWF replacement products in patients with VWF deficiency. Patients who have experienced reactions to VWF products may benefit from these protocols.

Publication types

  • Case Reports
  • Letter
  • Research Support, N.I.H., Extramural

MeSH terms

  • Child
  • Child, Preschool
  • Desensitization, Immunologic / methods*
  • Humans
  • Male
  • Siblings
  • Skin Tests
  • von Willebrand Disease, Type 3 / immunology*
  • von Willebrand Factor / adverse effects
  • von Willebrand Factor / immunology*

Substances

  • von Willebrand Factor