Successful treatment of postoperative multidrug-resistant Acinetobacter baumannii meningitis by tigecycline

J Glob Antimicrob Resist. 2016 Jun:5:62-3. doi: 10.1016/j.jgar.2015.12.003. Epub 2015 Dec 21.

Abstract

Tigecycline is a broad-spectrum antibiotic with activity against multidrug-resistant (MDR) bacteria. It has limited indications. Studies are necessary to elaborate new guidelines. Here we report a case of postoperative MDR Acinetobacter baumannii meningitis treated by tigecycline combined with colimycin for 21 days. The treatment was well tolerated with a favourable outcome. In conclusion, tigecycline was shown to be effective in a case of MDR A. baumannii meningitis.

Keywords: Acinetobacter baumannii; Nosocomial meningitis; Tigecycline.

Publication types

  • Case Reports

MeSH terms

  • Acinetobacter Infections / drug therapy*
  • Acinetobacter baumannii / drug effects*
  • Adult
  • Anti-Bacterial Agents / therapeutic use
  • Colistin
  • Drug Resistance, Multiple, Bacterial*
  • Humans
  • Male
  • Meningitis / drug therapy*
  • Meningitis / microbiology
  • Microbial Sensitivity Tests
  • Minocycline / analogs & derivatives*
  • Minocycline / therapeutic use
  • Tigecycline

Substances

  • Anti-Bacterial Agents
  • Tigecycline
  • Minocycline
  • Colistin