Trichoblastoma: is a clinical or dermoscopic diagnosis possible?

J Eur Acad Dermatol Venereol. 2016 Nov;30(11):1978-1980. doi: 10.1111/jdv.13830. Epub 2016 Jul 21.

Abstract

Background: Trichoblastoma is a rare benign skin tumour that must be differentiated from basal cell carcinoma for its benign course and favourable outcome.

Objectives: To describe clinical and dermoscopic features of solitary primitive trichoblastoma and to compare them with trichoblastic basal cell carcinoma (tBCC).

Methods: Digital dermoscopic images of 19 trichoblastoma and 19 tBCC were compared and reviewed by a dermatologist experienced in dermoscopy.

Results: The most striking dermoscopic difference between trichoblastoma and tBCC was the presence of blue-grey globules and blue-grey ovoid nests that were found to be more frequent but not exclusive of tBCC. Arborizing vessels were found both in trichoblastoma and tBCC, with a lower frequency in the latter.

Conclusion: Histology remains the gold standard to differentiate trichoblastoma from tBCC.

MeSH terms

  • Dermoscopy / methods*
  • Diagnosis, Differential
  • Humans
  • Skin Neoplasms / diagnosis*
  • Skin Neoplasms / pathology