ECG-triggered high-pitch CT for simultaneous assessment of the aorta and coronary arteries

J Cardiovasc Comput Tomogr. 2016 Sep-Oct;10(5):407-13. doi: 10.1016/j.jcct.2016.07.010. Epub 2016 Jul 12.

Abstract

Objectives: To study the image quality of ECG-gated-computed tomography (CT) acquisition with a high-pitch CT imaging for the exploration of both the aorta and coronary arteries.

Methods: Eighty-four patients underwent high-pitch ECG-gated aortic CT without β-blockers with iterative reconstruction algorithms. Contrast-to-noise ratio (CNR) between vessels and adjacent perivascular fat tissue were calculated on the aorta and the coronary arteries. Dose-length-products (DLP) were recorded. Two blinded readers graded image quality of the aorta and the coronary arteries on a 3-point scale. Coronary artery stenoses were compared with coronary angiograms in 24 patients. Kappa values were calculated.

Results: High-pitch acquisition resulted in a mean DLP of 234 ± 93 mGy cm(4.2 mSv) for an acquisition of the entire aorta, (mean 73 ± 16 bpm). CNR for ascending aorta was 10.6 ± 4 and CNR for coronary arteries was 9.85 ± 4.1. Image quality was excellent in 79/84 patients (94%), and excellent or moderate but diagnostic in 1087/1127 coronary artery segments (96%). 74 significant stenoses were observed, and 38/40 significant stenoses were confirmed by coronary angiography (K = 0.91, Sensitivity = 0.97, Specificity = 0.98).

Conclusion: High-pitch ECG-gated aortic CT with iterative reconstructions allows an accurate exploration of both aorta and coronary arteries during the same acquisition, with limited dose deposition, despite the lack of β-blockers and relatively high heart rate. Radiologists need to be aware of the necessity to analyze and report coronary artery disease in aortic examination.

Keywords: Aortic CTA; Cardiovascular imaging; Coronary CTA; ECG-gated high-pitch protocol; Iterative reconstructions.

MeSH terms

  • Adult
  • Aged
  • Aged, 80 and over
  • Algorithms
  • Aorta / diagnostic imaging*
  • Aorta / physiopathology
  • Aortic Diseases / diagnostic imaging*
  • Aortic Diseases / physiopathology
  • Aortic Valve / diagnostic imaging*
  • Aortic Valve / physiopathology
  • Aortography / methods*
  • Artifacts
  • Cardiac-Gated Imaging Techniques*
  • Computed Tomography Angiography*
  • Contrast Media / administration & dosage
  • Coronary Angiography / methods*
  • Coronary Stenosis / diagnostic imaging*
  • Coronary Stenosis / physiopathology
  • Coronary Vessels / diagnostic imaging*
  • Coronary Vessels / physiopathology
  • Electrocardiography*
  • Female
  • Humans
  • Male
  • Middle Aged
  • Multidetector Computed Tomography*
  • Observer Variation
  • Predictive Value of Tests
  • Radiation Dosage
  • Radiographic Image Interpretation, Computer-Assisted
  • Reproducibility of Results
  • Retrospective Studies
  • Signal-To-Noise Ratio
  • Young Adult

Substances

  • Contrast Media