Outcome analysis for prediction of early and long-term survival in patients receiving intra-aortic balloon pumping after cardiac surgery

Gen Thorac Cardiovasc Surg. 2016 Oct;64(10):584-91. doi: 10.1007/s11748-016-0679-3. Epub 2016 Jul 25.

Abstract

Background: Patients requiring an intra-aortic balloon pump (IABP) after cardiac surgery are critically ill and need a prolonged ICU stay. Considering limited health care resources, the early identification of patients with an extremely poor prognosis is important as a solid base for the decision whether further aggressive continuation or cessation of the therapy is recommendable.

Methods: From 2001 to 2007, 552 patients with low-output syndrome after open-heart surgery and IABP implantation in OR or within 24 h thereafter on ICU were retrospectively analyzed.

Results: The overall mortality at 30 and 180-day were 31 and 40 %, respectively. According to multivariate analyses, following factors were used to generate an IABP score: female gender, age ≥70 years, simultaneous coronary and valve surgery, aortic cross-clamp time >120 min., need of norepinephrin more than 0.4 µg kg(-1) min(-1), postoperative dialysis, and maximal serum creatinine kinase >3000 mg mL(-1). The 30-day mortality continuously increased along the score (10.1 % for score = 0, n = 98; 11.8 % for score = 1, n = 144; 27.5 % for score = 2, n = 153; 40.4 % score = 3, n = 89; 65.2 % for score = 4, n = 46; 77.8 % for score = 5, n = 27) and reached 100 % for all patients with a score of 6 (n = 4).

Conclusions: Prediction of 30 days mortality was possible with our scoring system based on multivariate analysis, and patients with scores of 4 or greater had remarkably worse early and late survival.

Keywords: Cardiac surgery; Intraaortic balloon pumping; Low output syndrome.

MeSH terms

  • Aged
  • Cardiac Output, Low / etiology
  • Cardiac Output, Low / therapy*
  • Cardiac Surgical Procedures / adverse effects*
  • Female
  • Heart-Assist Devices
  • Humans
  • Intra-Aortic Balloon Pumping / methods*
  • Male
  • Middle Aged
  • Multivariate Analysis
  • Postoperative Care / methods
  • Postoperative Period
  • Prognosis
  • Retrospective Studies
  • Risk Assessment / methods
  • Risk Factors
  • Survival Analysis
  • Treatment Outcome