Long-Term Use and Safety of Migraine Preventive Medications

Headache. 2016 Sep;56(8):1335-43. doi: 10.1111/head.12891. Epub 2016 Aug 1.

Abstract

Migraine preventive medications are used to reduce the frequency, severity, and disability of migraine attacks. Once migraine preventive therapy is initiated, the question of how long to maintain this therapy arises. This article will explore the literature pertaining to the long-term use of migraine preventive medications, including length of treatment and safety with long-term exposure.

Keywords: anticonvulsants; antidepressants; beta blockers; headache; migraine; preventive therapy.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Central Nervous System Agents / adverse effects*
  • Central Nervous System Agents / therapeutic use*
  • Female
  • Humans
  • Migraine Disorders / prevention & control*

Substances

  • Central Nervous System Agents