ATM mutations in major stereotyped subsets of chronic lymphocytic leukemia: enrichment in subset #2 is associated with markedly short telomeres

Haematologica. 2016 Sep;101(9):e369-73. doi: 10.3324/haematol.2016.142968. Epub 2016 Jun 16.
No abstract available

Keywords: ATM mutation; antigenic selection; chronic lymphocytic leukemia; short telomere; stereotyped subset.

Publication types

  • Letter
  • Multicenter Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Ataxia Telangiectasia Mutated Proteins / genetics*
  • Cohort Studies
  • Humans
  • Leukemia, Lymphocytic, Chronic, B-Cell / classification*
  • Leukemia, Lymphocytic, Chronic, B-Cell / genetics
  • Leukemia, Lymphocytic, Chronic, B-Cell / mortality
  • Mutation*
  • Sequence Analysis, DNA
  • Survival Analysis
  • Telomere / ultrastructure
  • Telomere Shortening*

Substances

  • ATM protein, human
  • Ataxia Telangiectasia Mutated Proteins