Secondary structure and (1)H, (13)C and (15)N resonance assignments of Skint-1: a selecting ligand for a murine γδ T cell subset implicated in tumour suppression

Biomol NMR Assign. 2016 Oct;10(2):357-60. doi: 10.1007/s12104-016-9700-0. Epub 2016 Aug 4.

Abstract

A study describing the (1)H, (13)C and (15)N backbone and side chain chemical shift assignments and secondary structure of Skint-1 a prototypic member of a family of mouse genes, of which Skint-1 is involved in the development of the dendritic epidermal T cell (DETC) subset of γδ T cells.

Keywords: Backbone resonance assignment; Dendritic epidermal T cells; Intraepithelial lymphocytes; NMR; Secondary structure; Skint-1; γδ T cells.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Immunoglobulins / chemistry*
  • Immunoglobulins / metabolism*
  • Ligands
  • Mice
  • Nuclear Magnetic Resonance, Biomolecular*
  • Protein Structure, Secondary
  • Substrate Specificity
  • T-Lymphocyte Subsets / metabolism*
  • Tumor Suppressor Proteins / chemistry*
  • Tumor Suppressor Proteins / metabolism*

Substances

  • Immunoglobulins
  • Ligands
  • Skint1 protein, mouse
  • Tumor Suppressor Proteins