A comprehensive analysis of genome-wide association studies to identify prostate cancer susceptibility loci for the Romanian population

Rom J Morphol Embryol. 2016;57(2):467-75.

Abstract

The aim of this study is to examine a large dataset of single nucleotide polymorphism known to be associated with prostate cancer from previous genome-wide association studies and create a dataset of single nucleotide polymorphisms that can be used in replication studies for the Romanian population. This study will define a list of markers showing a significant association with this phenotype. We propose the results of this study as a starting point for any Romanian genome-wide association studies researching the genetic susceptibility for prostate cancer.

MeSH terms

  • Genetic Loci*
  • Genetic Predisposition to Disease*
  • Genome-Wide Association Study*
  • Humans
  • Male
  • Polymorphism, Single Nucleotide / genetics
  • Prostatic Neoplasms / genetics*
  • Romania