Predictors of radio-cephalic arteriovenous fistulae patency in an Asian population

J Vasc Access. 2016 Sep 21;17(5):411-416. doi: 10.5301/jva.5000591. Epub 2016 Aug 2.

Abstract

Purpose: To identify predictors of arteriovenous fistula (AVF) patency in Asian patients with autogenous radio-cephalic arteriovenous fistula (RCAVF).

Methods: Retrospective review of 436 RCAVFs created between 2009 and 2013. Predictors of patency were identified with univariate and multivariate analysis. Kaplan-Meier survival analysis and log-rank test were used to calculate patency rates.

Results: Overall secondary patency rate was 72% at 12 months, 69% at 24 months, 58% at 36 months, 57% at 48 months, 56% at 60 months and 54% at 72 months. Univariate analysis showed that factors which predict for patency include male gender (p = 0.003), good diabetic control (p = 0.025), aspirin use (p = 0.031), pre-dialysis status (p = 0.037), radial artery diameter (p = 0.029) and non-calcified radial arteries (p = 0.002). Age (p = 0.866), cephalic vein diameter (p = 0.630) and surgeon grade (p = 0.472) did not predict for primary AVF failure. Multivariate analysis revealed the male gender to be an independent predictor for patency (odds ratio 1.99, p = 0.01). Subset analysis showed a significantly larger average radial artery diameter of 2.3 mm amongst males, as compared to 1.9 mm amongst females (p = 0.001) and no statistical difference in the average cephalic vein diameter.

Conclusions: Within our Asian study population, 12-month patency rate of RCAVF is 72%, 69% at 24 months, 58% at 36 months, 57% at 48 months, 56% at 60 months and 54% at 72 months. Male gender is an independent predictor for RCAVF patency. In females or patients with calcified radial arteries, a more proximal AVF should be considered.

MeSH terms

  • Adult
  • Aged
  • Aged, 80 and over
  • Arteriovenous Shunt, Surgical* / adverse effects
  • Asian People*
  • Chi-Square Distribution
  • Female
  • Graft Occlusion, Vascular / diagnosis
  • Graft Occlusion, Vascular / ethnology
  • Graft Occlusion, Vascular / physiopathology
  • Humans
  • Kaplan-Meier Estimate
  • Logistic Models
  • Male
  • Middle Aged
  • Multivariate Analysis
  • Odds Ratio
  • Radial Artery / diagnostic imaging
  • Radial Artery / physiopathology
  • Radial Artery / surgery*
  • Renal Dialysis*
  • Retrospective Studies
  • Risk Factors
  • Sex Factors
  • Singapore / epidemiology
  • Time Factors
  • Treatment Outcome
  • Upper Extremity / blood supply*
  • Vascular Calcification / ethnology
  • Vascular Patency*
  • Veins / diagnostic imaging
  • Veins / physiopathology
  • Veins / surgery*
  • Young Adult