Repackaging of Intravenous Fat Emulsions: A Clinical Conundrum

Nutr Clin Pract. 2016 Oct;31(5):642-6. doi: 10.1177/0884533616662994. Epub 2016 Aug 12.

Abstract

To accommodate small fluid volumes, repackaging of intravenous fat emulsions (IVFEs) is frequently performed in institutions providing parenteral nutrition to neonates and smaller pediatric patients. However, some consider this an unsafe practice. Concerns for potential administration errors leading to an overdose of IVFEs are weighed against the potential for microbial contamination from the repackaging process. The clinician providing pediatric nutrition support should tailor repackaging practices to ensure patient safety and quality. This discussion aims to describe the strengths and limitations surrounding IVFE repackaging to provide guidance regarding the practice.

Keywords: intravenous fat emulsions; neonates; parenteral nutrition; parenteral nutrition solutions; pediatrics.

Publication types

  • Review

MeSH terms

  • Drug Packaging / methods*
  • Fat Emulsions, Intravenous / administration & dosage*
  • Humans
  • Infant
  • Infant, Newborn
  • Medication Errors / prevention & control*
  • Parenteral Nutrition / methods*

Substances

  • Fat Emulsions, Intravenous