An exploration of the potential utility of fetal cardiovascular MRI as an adjunct to fetal echocardiography

Prenat Diagn. 2016 Oct;36(10):916-925. doi: 10.1002/pd.4912. Epub 2016 Aug 31.

Abstract

Objectives: Fetal cardiovascular magnetic resonance imaging (MRI) offers a potential alternative to echocardiography, although in practice, its use has been limited. We sought to explore the need for additional imaging in a tertiary fetal cardiology unit and the usefulness of standard MRI sequences.

Methods: Cases where the diagnosis was not fully resolved using echocardiography were referred for MRI. Following a three-plane localiser, fetal movement was assessed with a balanced steady-state free precession (bSSFP) cine. Single-shot fast spin echo and bSSFP sequences were used for diagnostic imaging.

Results: Twenty-two fetal cardiac MRIs were performed over 12 months, at mean gestation of 32 weeks (26-38 weeks). The majority of referrals were for suspected vascular abnormalities (17/22), particularly involving the aortic arch (n = 10) and pulmonary vessels (n = 4). Single-shot fast spin echo sequences produced 'black-blood' images, useful for examining the extracardiac vasculature in these cases. BSSFP sequences were more useful for intracardiac structures. Real-time SSFP allowed for dynamic assessment of structures such as cardiac masses, with enhancement patterns also allowing for tissue characterisation in these cases.

Conclusions: Fetal vascular abnormalities such as coarctation can be difficult to diagnose by using ultrasound. Fetal MRI may have an adjunctive role in the evaluation of the extracardiac vascular anatomy and tissue characterisation. © 2016 The Authors. Prenatal Diagnosis published by John Wiley & Sons, Ltd.

MeSH terms

  • Aorta, Thoracic / abnormalities
  • Aorta, Thoracic / diagnostic imaging
  • Aortic Coarctation / diagnostic imaging
  • Diverticulum / diagnostic imaging
  • Echocardiography / methods*
  • Female
  • Fetal Heart / abnormalities
  • Fetal Heart / diagnostic imaging*
  • Heart Defects, Congenital / diagnostic imaging*
  • Heart Septal Defects, Ventricular / diagnostic imaging
  • Humans
  • Magnetic Resonance Imaging / methods*
  • Pregnancy
  • Pregnancy Trimester, Second
  • Pregnancy Trimester, Third
  • Prenatal Diagnosis
  • Pulmonary Artery / abnormalities
  • Pulmonary Artery / diagnostic imaging
  • Pulmonary Veins / abnormalities
  • Pulmonary Veins / diagnostic imaging
  • Ultrasonography, Prenatal