[Radiotherapy of hypopharynx cancers]

Cancer Radiother. 2016 Sep:20 Suppl:S126-30. doi: 10.1016/j.canrad.2016.07.020. Epub 2016 Aug 10.
[Article in French]

Abstract

The intensity-modulated radiotherapy is the gold standard in the treatment of hypopharynx cancers. Early T1 and T2 tumours could be treated by exclusive radiotherapy or surgery. For tumours requiring total pharyngolaryngectomy (T2 or T3), induction chemotherapy followed by exclusive radiotherapy or concurrent chemoradiotherapy are possible. For T4 tumours, surgery must be proposed. The treatment of lymph nodes is based on the initial treatment of the primary tumour. In non-surgical procedure, in case of sequential radiotherapy, curative dose is 70Gy and prophylactic dose is 50Gy. An integrated simultaneous boost radiotherapy is allowed (70Gy in 2Gy per fraction and 56Gy in 1.8Gy per fraction or 70Gy in 2.12Gy per fraction). Postoperatively, radiotherapy is used for locally advanced cancers with dose levels based on pathologic criteria (66Gy for R1 resection, 50 to 54Gy for complete resection). Volume delineation is based on guidelines.

Keywords: Delineation; Dose; Doses; Délinéation; Hypopharynx cancer; Indication; Indications; Intensity-modulated radiotherapy; Radiothérapie conformationnelle avec modulation d’intensité; Tumeurs hypopharyngées.

Publication types

  • Practice Guideline

MeSH terms

  • Chemoradiotherapy
  • Combined Modality Therapy
  • Dose Fractionation, Radiation
  • Humans
  • Hypopharyngeal Neoplasms / drug therapy
  • Hypopharyngeal Neoplasms / radiotherapy*
  • Hypopharyngeal Neoplasms / surgery
  • Lymphatic Irradiation
  • Lymphatic Metastasis
  • Organs at Risk
  • Radiation Injuries / prevention & control
  • Radiotherapy Dosage
  • Radiotherapy Planning, Computer-Assisted
  • Radiotherapy, Adjuvant / methods
  • Radiotherapy, Image-Guided / methods
  • Radiotherapy, Intensity-Modulated / adverse effects
  • Radiotherapy, Intensity-Modulated / methods*
  • Radiotherapy, Intensity-Modulated / standards